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Thermo Scientific Alfa Aesar 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, 98+%

CAS: 25952-53-8 | C8H18ClN3 | 191.70 g/mol

Overview
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Additional Details:
Additional Details: CAS Number: 25952-53-8 Weight: 0.02500kg Transport: UN number : 2811 Chem class : 6.1 Pack group : III


Quantity 25 g

Disclaimers: RUO – Research Use Only

Product Code. 11429742

Quantity Price
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  • Description and Specification
  • Alternative Products
  • Documentation
  • Safety and Handling
Description and Specification

Chemical Identifiers

CAS 25952-53-8
Molecular Formula C8H18ClN3
Molecular Weight (g/mol) 191.70
MDL Number MFCD00012503
InChI Key FPQQSJJWHUJYPU-UHFFFAOYSA-N
Synonym 1-3-dimethylaminopropyl-3-ethylcarbodiimide hydrochloride,edc.hcl,edci,edc hydrochloride,wsc hcl,edac hydrochloride,edac, hydrochloride,1-ethyl-3-3-dimethylaminopropyl carbodiimide hydrochloride,edcl,edac hcl
PubChem CID 2723939
IUPAC Name 3-(ethyliminomethylideneamino)-N,N-dimethylpropan-1-amine;hydrochloride
SMILES Cl.CCN=C=NCCCN(C)C

Specification

Chemical Name or Material 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide Hydrochloride
CAS 25952-53-8
Melting Point ∼113°C
Molecular Formula C8H18ClN3
Linear Formula CH3CH2N=C=N(CH2)3N(CH3)2·HCl
MDL Number MFCD00012503
Quantity 25 g
Beilstein 5764110
Sensitivity Moisture sensitive
Synonym 1-3-dimethylaminopropyl-3-ethylcarbodiimide hydrochloride,edc.hcl,edci,edc hydrochloride,wsc hcl,edac hydrochloride,edac, hydrochloride,1-ethyl-3-3-dimethylaminopropyl carbodiimide hydrochloride,edcl,edac hcl
Synonym 1-3-dimethylaminopropyl-3-ethylcarbodiimide hydrochloride,edc.hcl,edci,edc hydrochloride,wsc hcl,edac hydrochloride,edac, hydrochloride,1-ethyl-3-3-dimethylaminopropyl carbodiimide hydrochloride,edcl,edac hcl
Synonym 1-3-dimethylaminopropyl-3-ethylcarbodiimide hydrochloride,edc.hcl,edci,edc hydrochloride,wsc hcl,edac hydrochloride,edac, hydrochloride,1-ethyl-3-3-dimethylaminopropyl carbodiimide hydrochloride,edcl,edac hcl
Synonym 1-3-dimethylaminopropyl-3-ethylcarbodiimide hydrochloride,edc.hcl,edci,edc hydrochloride,wsc hcl,edac hydrochloride,edac, hydrochloride,1-ethyl-3-3-dimethylaminopropyl carbodiimide hydrochloride,edcl,edac hcl
Synonym 1-3-dimethylaminopropyl-3-ethylcarbodiimide hydrochloride,edc.hcl,edci,edc hydrochloride,wsc hcl,edac hydrochloride,edac, hydrochloride,1-ethyl-3-3-dimethylaminopropyl carbodiimide hydrochloride,edcl,edac hcl
Synonym 1-3-dimethylaminopropyl-3-ethylcarbodiimide hydrochloride,edc.hcl,edci,edc hydrochloride,wsc hcl,edac hydrochloride,edac, hydrochloride,1-ethyl-3-3-dimethylaminopropyl carbodiimide hydrochloride,edcl,edac hcl
Synonym 1-3-dimethylaminopropyl-3-ethylcarbodiimide hydrochloride,edc.hcl,edci,edc hydrochloride,wsc hcl,edac hydrochloride,edac, hydrochloride,1-ethyl-3-3-dimethylaminopropyl carbodiimide hydrochloride,edcl,edac hcl
Synonym 1-3-dimethylaminopropyl-3-ethylcarbodiimide hydrochloride,edc.hcl,edci,edc hydrochloride,wsc hcl,edac hydrochloride,edac, hydrochloride,1-ethyl-3-3-dimethylaminopropyl carbodiimide hydrochloride,edcl,edac hcl
Synonym 1-3-dimethylaminopropyl-3-ethylcarbodiimide hydrochloride,edc.hcl,edci,edc hydrochloride,wsc hcl,edac hydrochloride,edac, hydrochloride,1-ethyl-3-3-dimethylaminopropyl carbodiimide hydrochloride,edcl,edac hcl
Synonym 1-3-dimethylaminopropyl-3-ethylcarbodiimide hydrochloride,edc.hcl,edci,edc hydrochloride,wsc hcl,edac hydrochloride,edac, hydrochloride,1-ethyl-3-3-dimethylaminopropyl carbodiimide hydrochloride,edcl,edac hcl
Solubility Information Soluble in acetonitrile dichloromethane,dimethylformamide,and tetrahydrofuran. Slightly soluble in water.
InChI Key FPQQSJJWHUJYPU-UHFFFAOYSA-N
SMILES Cl.CCN=C=NCCCN(C)C
IUPAC Name 3-(ethyliminomethylideneamino)-N,N-dimethylpropan-1-amine;hydrochloride
Molecular Weight (g/mol) 191.70
PubChem CID 2723939
Formula Weight 191.7
Percent Purity ≥98%

Applications
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is used as a carboxyl activating agent. It is used in peptide synthesis, 3′-amino-3′-deoxyadenosine-5′-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.

Solubility
Soluble in acetonitrile dichloromethane, dimethylformamide, and tetrahydrofuran. Slightly soluble in water.

Notes
Sensitive to moisture. Incompatible with strong acids, strong oxidizing agents and moisture.

Alternative Products
Documentation

Technical documents

Safety and Handling

[1-(3-Dimethylaminopropyl)-3-ethylcarbodiimidehydrochloride]

[Warning]

[{code=SKIN IRRIT. 2, sequence=1, description=Skin corrosion/irritation Category 2}, {code=EYE DAM. 2, sequence=2, description=Serious eye damage/eye irritation Category 2}, {code=STOT SE 3, sequence=3, description=Specific target organ toxicity Category 3}]

[{code=H315, sequence=1, description=Causes skin irritation.}, {code=H319, sequence=2, description=Causes serious eye irritation.}, {code=H335, sequence=3, description=May cause respiratory irritation.}]

[{code=P261, sequence=51, description=Avoid breathing dust/fume/gas/mist/vapours/spray.}, {code=P280, sequence=52, description=Wear protective gloves/protective clothing/eye protection/face protection.}, {code=P305+P351+P338, sequence=53, description=IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.}, {code=P304+P340, sequence=54, description=IF INHALED: Remove person to fresh air and keep comfortable for breathing.}, {code=P405, sequence=55, description=Store locked up.}, {code=P501, sequence=56, description=Dispose of contents/container to .}]

[{code=GHS07, sequence=1, description=EXCLAMATION MARK}]


Product Identifier
  • 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimidehydrochloride

Signal Word
  • Warning

Hazard Category
  • Skin corrosion/irritation Category 2
  • Serious eye damage/eye irritation Category 2
  • Specific target organ toxicity Category 3

Hazard Statement
  • H315- Causes skin irritation.
  • H319- Causes serious eye irritation.
  • H335- May cause respiratory irritation.

Precautionary Statement
  • P261- Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P280- Wear protective gloves/protective clothing/eye protection/face protection.
  • P305+P351+P338- IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P304+P340- IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P405- Store locked up.
  • P501- Dispose of contents/container to .