COMT Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

£135.0 - £349.0

Specification

Antigen COMT
Concentration 0.19 mg/mL
Applications Flow Cytometry,Immunocytochemistry,Immunofluorescence,Immunohistochemistry (Paraffin),Immunoprecipitation
Classification Polyclonal
Conjugate Unconjugated
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Specification

Antigen COMT
Concentration 0.19 mg/mL
Applications Flow Cytometry,Immunocytochemistry,Immunofluorescence,Immunohistochemistry (Paraffin),Immunoprecipitation
Classification Polyclonal
Conjugate Unconjugated
Form Liquid
Host Species Rabbit
Regulatory Status RUO
Target Species Human,Mouse,Rat
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No. O88587, P21964, P22734
Gene Alias catechol O methyltransferase, COMT
Gene ID (Entrez) 12846, 1312, 24267
Gene Symbols COMT
Immunogen COMT Fusion Protein Ag6502
Isotype IgG
Primary or Secondary Primary
Purification Method Antigen Affinity Chromatography
Content And Storage -20°C
Product Type Antibody
Gene COMT

COMT (Catechol-O-methyltransferase) catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.

Product Code Brand Quantity Price ??product.searchResults.label.quantityAvail??
Quantity
16823564
Proteintech
14754-1-AP-20UL
20 μL £135.0
20µL
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16813564
Proteintech
14754-1-AP-150UL
150 μL £349.0
150µL
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