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Di-tert-butyl dicarbonate, 97+%, Thermo Scientific Chemicals

£24.7 - £232.12

Chemical Identifiers

CAS 24424-99-5
Molecular Formula C10H18O5
Molecular Weight (g/mol) 218.249
MDL Number MFCD00008805
InChI Key DYHSDKLCOJIUFX-UHFFFAOYSA-N
Synonym di-tert-butyl dicarbonate,boc anhydride,boc-anhydride,di-t-butyl dicarbonate,di-tert-butyl pyrocarbonate,bis tert-butoxycarbonyl oxide,di-tert-butyldicarbonate,boc2o,di-t-butyl pyrocarbonate,di tert-butyl carbonate
PubChem CID 90495
ChEBI CHEBI:48500
IUPAC Name tert-butyl (2-methylpropan-2-yl)oxycarbonyl carbonate
SMILES CC(C)(C)OC(=O)OC(=O)OC(C)(C)C
View More Specs

Disclaimers: RUO – Research Use Only


Specification

Chemical Name or Material Di-tert-butyl dicarbonate
CAS 24424-99-5
Melting Point 21°C to 24°C
Density 0.95
Boiling Point 56°C to 57°C (0.5 mmHg)
Flash Point 37°C (99°F)
Assay Percent Range ≥97%
Odor Mild
Molecular Formula C10H18O5
Refractive Index 1.409
MDL Number MFCD00008805
Quantity 25 g
UN Number UN2930
Beilstein 1911173
Sensitivity Moisture sensitive
Synonym di-tert-butyl dicarbonate,boc anhydride,boc-anhydride,di-t-butyl dicarbonate,di-tert-butyl pyrocarbonate,bis tert-butoxycarbonyl oxide,di-tert-butyldicarbonate,boc2o,di-t-butyl pyrocarbonate,di tert-butyl carbonate
Synonym di-tert-butyl dicarbonate,boc anhydride,boc-anhydride,di-t-butyl dicarbonate,di-tert-butyl pyrocarbonate,bis tert-butoxycarbonyl oxide,di-tert-butyldicarbonate,boc2o,di-t-butyl pyrocarbonate,di tert-butyl carbonate
Synonym di-tert-butyl dicarbonate,boc anhydride,boc-anhydride,di-t-butyl dicarbonate,di-tert-butyl pyrocarbonate,bis tert-butoxycarbonyl oxide,di-tert-butyldicarbonate,boc2o,di-t-butyl pyrocarbonate,di tert-butyl carbonate
Synonym di-tert-butyl dicarbonate,boc anhydride,boc-anhydride,di-t-butyl dicarbonate,di-tert-butyl pyrocarbonate,bis tert-butoxycarbonyl oxide,di-tert-butyldicarbonate,boc2o,di-t-butyl pyrocarbonate,di tert-butyl carbonate
Synonym di-tert-butyl dicarbonate,boc anhydride,boc-anhydride,di-t-butyl dicarbonate,di-tert-butyl pyrocarbonate,bis tert-butoxycarbonyl oxide,di-tert-butyldicarbonate,boc2o,di-t-butyl pyrocarbonate,di tert-butyl carbonate
Synonym di-tert-butyl dicarbonate,boc anhydride,boc-anhydride,di-t-butyl dicarbonate,di-tert-butyl pyrocarbonate,bis tert-butoxycarbonyl oxide,di-tert-butyldicarbonate,boc2o,di-t-butyl pyrocarbonate,di tert-butyl carbonate
Synonym di-tert-butyl dicarbonate,boc anhydride,boc-anhydride,di-t-butyl dicarbonate,di-tert-butyl pyrocarbonate,bis tert-butoxycarbonyl oxide,di-tert-butyldicarbonate,boc2o,di-t-butyl pyrocarbonate,di tert-butyl carbonate
Synonym di-tert-butyl dicarbonate,boc anhydride,boc-anhydride,di-t-butyl dicarbonate,di-tert-butyl pyrocarbonate,bis tert-butoxycarbonyl oxide,di-tert-butyldicarbonate,boc2o,di-t-butyl pyrocarbonate,di tert-butyl carbonate
Synonym di-tert-butyl dicarbonate,boc anhydride,boc-anhydride,di-t-butyl dicarbonate,di-tert-butyl pyrocarbonate,bis tert-butoxycarbonyl oxide,di-tert-butyldicarbonate,boc2o,di-t-butyl pyrocarbonate,di tert-butyl carbonate
Synonym di-tert-butyl dicarbonate,boc anhydride,boc-anhydride,di-t-butyl dicarbonate,di-tert-butyl pyrocarbonate,bis tert-butoxycarbonyl oxide,di-tert-butyldicarbonate,boc2o,di-t-butyl pyrocarbonate,di tert-butyl carbonate
Solubility Information Miscible with decalin,toluene,carbon tetrachloride,tetrahydrofuran,dioxane,alcohols,acetone,acetonitrile and dimethylformamide. Immiscible with water.
InChI Key DYHSDKLCOJIUFX-UHFFFAOYSA-N
SMILES CC(C)(C)OC(=O)OC(=O)OC(C)(C)C
IUPAC Name tert-butyl (2-methylpropan-2-yl)oxycarbonyl carbonate
Molecular Weight (g/mol) 218.249
PubChem CID 90495
ChEBI CHEBI:48500
Formula Weight 218.25
Percent Purity ≥97%

Applications
Reagent for the introduction of the Boc protecting group.Di-tert-butyl dicarbonate is a reagent used for the introduction of BOC protecting group. It plays an important role in the preparation of 6-acetyl-1,2,3,4-tetrahydropyridine by reacting with 2-piperidone. It serves as a protecting group used in solid phase peptide synthesis.

Solubility
Miscible with decalin, toluene, carbon tetrachloride, tetrahydrofuran, dioxane, alcohols, acetone, acetonitrile and dimethylformamide. Immiscible with water.

Notes
Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Moisture and light sensitive. Incompatible with oxidizing agents, reducing agents, bases and acids.

  Product Code Brand Quantity Price ??product.searchResults.label.quantityAvail??
Quantity
11477726


Safety data sheet (SDS) 		Thermo Scientific Alfa Aesar
A14708.14
 25 g £27.38
25g
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11421950


Safety data sheet (SDS) 		Thermo Scientific Alfa Aesar
A14708.22
 100 g £75.25
100g
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11497726


Safety data sheet (SDS) 		Thermo Scientific Alfa Aesar
A14708.36
 500 g £232.12
500g
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** 11411950
Thermo Scientific Alfa Aesar
A14708.14
 25 g n/a  
** 11431950
Thermo Scientific Alfa Aesar
A14708.36
 500 g n/a  
** 11487726
Thermo Scientific Alfa Aesar
A14708.22
 100 g n/a  
** No longer available. See item for replacement.

Product Identifier
  • Di-tert-butyl dicarbonate

Signal Word
  • Danger

Hazard Category
  • Acute toxicity Category 1
  • Serious eye damage/eye irritation Category 1
  • Flammable solid Category 2
  • Skin corrosion/irritation Category 2
  • Skin sensitiser Category 1
  • Specific target organ toxicity Category 3

Hazard Statement
  • H228- Flammable solid.
  • H315- Causes skin irritation.
  • H317- May cause an allergic skin reaction.
  • H318- Causes serious eye damage.
  • H330- Fatal if inhaled.
  • H335- May cause respiratory irritation.

Precautionary Statement
  • P210- Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P280- Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352- IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340- IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P305+P351+P338- IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P310- Immediately call a POISON CENTER/doctor/.
  • P332+P313- If skin irritation occurs: Get medical advice/attention.

Supplemental Information
  • MIXTURE LIST- Contains : Di-tert-butyl dicarb