missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Beskrivelse
PINK1 (PTEN-induced putative kinase 1) protects from mitochondrial dysfunction in cells by conferring different autophosphorylation activity to mitochondrial genes. The kinase domain of PINK1 appears to be critical in its protective effects. Mitochondrial proteins are critical for the regulation of cellular energy and adaptation to stress. Particularly in brain cells, mitochondrial demand is extraordinarily high, in order to accommodate aerobic and anaerobic support of high energy processes. When mitochondrial structure and/or function is disrupted in the brain, neurodegenerative diseases like Parkinson′s disease are triggered.
Tekniske data
Tekniske data
| Antigene | PINK1 |
| Applicazioni | Immunofluorescence, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot |
| Classificazione | Polyclonal |
| Concentrazione | 0.2 mg/mL |
| Coniugato | Unconjugated |
| Formulazione | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | PINK1 |
| N. accesso geni | Q99MQ3, Q9BXM7 |
| Alias gene | BRPK, PARK6, PINK1, PTEN induced putative kinase 1 |
| Simboli geni | PINK1 |
| Vis mere |
Produkttitel
Ved at klikke på Send, anerkender du, at du kan blive kontaktet af Fisher Scientific med hensyn til den feedback, du har givet i denne formular. Vi deler ikke dine oplysninger til andre formål. Alle angivne kontaktoplysninger skal også vedligeholdes i overensstemmelse med vores Privatlivspolitik.
Ser du en mulighed for forbedring?