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CD71 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

£135.0 - £349.0

Specification

Antigen CD71
Concentration 0.19 mg/mL
Applications Immunofluorescence,Immunoprecipitation,Immunohistochemistry (Paraffin),Western Blot,Immunocytochemistry
Classification Polyclonal
Conjugate Unconjugated
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Specification

Antigen CD71
Concentration 0.19 mg/mL
Applications Immunofluorescence,Immunoprecipitation,Immunohistochemistry (Paraffin),Western Blot,Immunocytochemistry
Classification Polyclonal
Conjugate Unconjugated
Form Liquid
Host Species Rabbit
Regulatory Status RUO
Target Species Human
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No. P02786
Gene Alias CD71, p90, sTfR, T9, TFR, TFR1, TFRC, TR, Transferrin receptor protein 1, TRFR
Gene ID (Entrez) 7037
Gene Symbols TFRC
Immunogen CD71 Fusion Protein Ag0123
Isotype IgG
Primary or Secondary Primary
Purification Method Antigen Affinity Chromatography
Content And Storage -20°C
Product Type Antibody
Gene TFRC

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregcy, irritable bowel syndrome and in HIV patients.

Product Code Brand Quantity Price ??product.searchResults.label.quantityAvail??
Quantity
16876233
Proteintech
10084-2-AP-20UL
 20 μL £135.0
20µL
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16866233
Proteintech
10084-2-AP-150UL
 150 μL £349.0
150µL
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